Mao Li, Viktoriya Coneva, David Clark, Dan Chitwood, Margaret Frank. Quantitative dissection of color patterning in the foliar ornamental Coleus reveals underlying features driving aesthetic value. (2021). BioRxiv.

Williams, Brandon, Muhammad Umair Ahsan, and Margaret H. Frank. (2021). Getting to the root of grafting-induced traits.  Current Opinion in Plant Biology 59: 101988.



Li Chengjie Chen, Hao Chen, Yi Zhang, Hannah R.Thomas, Margaret H.Frank, Yehua He, and Rui Xia (2020) TBtools - an integrative toolkit developed for interactive analyses of big biological data. Molecular Plant. In Press.

Preprint available on BioRxiv: 

Download TBtools HERE:

**Tutorials coming soon**

Daniel H. Chitwood, Joey Mullins, Zoë Migicovsky, Margaret H. Frank, Robert VanBuren, Jason P. Londo (2020) Vein-to-blade ratio is an allometric indicator of climate-induced changes in grapevine leaf size and shape.  

BioRxiv 2020.05.20.106906; doi:

Abigail E. Bryson et al. (2020) Composite modeling of leaf shape across shoots discriminates Vitis species better than individual leaves.

BioRxiv 2020.06.22.163899; doi:



Li Li, M, Frank, MH, and Migicovsky, Z (2019) ColourQuant: a high-throughput technique to extract and quantify colour phenotypes from plant images. AriXiv and In Review for Springer Books

Thomas, HR and Frank, MH (2019) Connecting the pieces: uncovering the molecular basis for long-distance communication through plant grafting. New Phytologist. 223(2): 582-589.




Lee, J-Y and Frank, MH (2018) Plasmodesmata in phloem: different gateways for different cargoes. Current Opinion in Plant Biology 43:119-124

DOI: 10.1016/j.pbi.2018.04.014

Li, M, Frank, MH, Coneva, V, Mio, W, Topp, CN, and Chitwood, DH (2018) The persistent homology mathematical framework provides enhanced genotype-to-phenotype associations for plant morphology. Plant Physiology

DOI: 10.1104/pp.18.00104

Li, M, An, H, Angelovici, R, Bagaza, C, Batushansky, A, Clark, L, Coneva, V, Donoghue, MJ, Edwards, E, Fajardo, D, Fang, H, Frank, MH, Gallaher, T, Gebken, S, Hill, T, Jansky, S, Kaur, B, Klahs, PC, Klein, LL, Kuraparthy, V, Londo, J, Migicovsky, Z, Miller, A, Mohn, R, Myles, S, Otoni, WC, Pires, JC, Rieffer, E, Schmerler, S, Spriggs, E, Topp, CN, Van Deynze, A, Zhang, K, Zhu, L, Zink, BM, and Chitwood DH (2018) Topological Data Analysis as a Morphometric Method: Using Persistent Homology to Demarcate a Leaf Morphospace. Frontiers in Plant Science 553

DOI: 10.3389/fpls.2018.00553




Coneva, V, Frank, MH, de Luis Balaguer, MA, Sozzani, R, and Chitwood, DH (2017) Genetic architecture and molecular networks underlying leaf thickness in desert-adapted tomato Solanum pennellii. Plant Physiology 175(1):376-391.

DOI: 10.1104/pp.17.00790

Andres, RJ, Coneva, V, Frank, MH, Tuttle, JR, Han, S-W, Samayoa, LF, Kaur, B, Zhu, L, Fang, H, Bowman, DT, Rojas- Pierce, M, Haigler, CH, Jones, DC, Holland, JB, Chitwood, DH, and Kuraparthy, V. Modifications to a LATE MERISTEM IDENTITY-1 gene are responsible for the major leaf shapes of Upland cotton (Gossypium hirsutum L.). Proceedings of the National Academy of Sciences Plus 114(1):E57-E66.

DOI: 10.1073/pnas.1613593114


Frank, MH and Chitwood, DH (2016) Plant Chimeras: the good, the bad, and the ‘Bizzaria’. Developmental Biology 419: 41-53.

DOI: 10.1016/j.ydbio.2016.07.003

Warschefsky, EJ, Klein, LL, Frank, MH, Chitwood, DH, Londo, JP, von Wettberg, EJB, and Miller, AJ (2016) Rootstocks: Diversity, Domestication, and Impacts on Shoot Phenotypes. Trends in Plant Science 21: 418-37.

DOI: 10.1016/j.tplants.2015.11.008


Frank, MH and Scanlon, MJ (2015) Cell-Specific Transcriptomic Analyses of 3-Dimensional Shoot Development in the moss Physcomitrella patens. The Plant Journal 83: 743-751.

DOI: 10.1111/tpj.12928

Frank, MH, Edwards, MB, Schultz, ER, McKain, MR, Fei, Z, Sorensen, I, Rose, JKC, Scanlon, MJ (2015) Dissecting the molecular signatures of apical cell-type shoot meristems from two ancient land plant lineages. New Phytologist 207: 893-904.

DOI: 10.1111/nph.13407

Frank, MH and Scanlon MJ (2015) Transcriptomic Evidence for the Evolution of Shoot Meristem Function in Sporophyte-Dominant Land Plants through Concerted Selection of Ancestral Gametophytic and Sporophytic Genetic Programs. Molecular Biology and Evolution 32: 355-367.

DOI: 10.1093/mol- bev/msv182